What is Sculptra?

SCULPTRA is an injectable collagen-stimulating substance containing PLLA (Poly-L-Lactic Acid) particles. It stimulates collagen production, plumps, and lifts the face, with effects lasting up to two years. It particularly targets the production of Collagen Type I, one of the more than 16 types of collagen produced by the body, accounting for over 90% of all collagen. Collagen helps improve elasticity, promotes wound healing, and is found in the skin, hair, bones, tissues, and blood vessel walls. SCULPTRA can stimulate up to 66.5% increase in Collagen Type I production three months after injection. PLLA is considered the first collagen-stimulating substance, or "biostimulator," approved by the U.S. Food and Drug Administration (FDA) in 1999. It is a synthetic substance derived from natural plants, has no side effects, is safe, and is biodegradable. It is also used in the production of dissolvable sutures, screws, and plates used for bone fixation. It helps restore the deep layers of the skin to lift and reduce wrinkles, making the skin appear younger than its actual age. [https://youtu.be/N8fZs-b8wjw] SCULPTRA is mixed with sterile water before being injected into the subcutaneous layer of the skin, primarily in the temples, cheeks, and under the cheekbones. The substance spreads throughout the skin layers. PLLA increases the number of fibroblast cells, which are responsible for producing two proteins: collagen and elastin. These proteins help strengthen the internal skin structure and support the dermis, the middle layer of skin composed of elastic connective tissue. In this area, a large number of fibroblast cells are found. Furthermore, PLLA transforms into lactic acid, an acid in the same family as AHA, which helps exfoliate dead skin cells, revealing brighter, smoother skin. This stimulates collagen synthesis through the action of white blood cells called macrophages, which are responsible for eliminating foreign substances from the body. As a result, PLLA gradually breaks down, but the collagen remains, helping to reduce the appearance of wrinkles and fine lines. The effects can be felt from the first week after treatment, and collagen production continues to be stimulated.