Can I get Botox injections along with Ulthera Prime or Xtherma? Which should be done first?

A Botox program combined with XTherma and Ultherapy Prime for facial lifting and contouring, available at a beauty clinic in Bangkok.

Many people have become interested in the subject. Non-surgical facelift It's often not just about sagging skin that's a concern, but a whole host of other problems. Wrinkles from muscle movement, an undefined facial contour, slightly sagging cheeks, or skin that doesn't look as firm as before. Therefore, a very common question we encounter in clinics is, "If I get the injection..." Botox Whether you already have Botox or are planning to get it, you can do it in conjunction with other treatments. Ulthera Prime or XTherma Is it possible? And if so, what should we do first?

list of contents

  1. What are the differences between Botox, Ulthera Prime, and XTherma?
  2. Can Botox be combined with Ulthera Prime?
  3. Can Botox be combined with XTherma?
  4. If you're doing them together, which one should you do first?
  5. In what cases should you take a break and not rush through something consecutively?
  6. Choose the plan that best suits your goals.
  7. Simple summary
  8. FAQ (Frequently Asked Questions)

What are the differences between Botox, Ulthera Prime, and XTherma?

Before answering the question of order, it's important to understand that these three things do not serve the same function.

Botox: An injection program to reduce wrinkles and reshape the face.

Botox It is a group of botulinum neurotoxins used to reduce the activity of certain muscles, and therefore is often discussed in the context of wrinkles caused by facial expressions.

For example, it can be used on the forehead, between the eyebrows, and around the eyes, or on other areas as per the doctor's plan, such as the masseter brow bone, lower face, or intradermal BoNT in some cases to help with skin quality, sebum, pores, or erythema according to specific guidelines.

Ultherapy Prime is a non-surgical facelift device. Using MFU-V technology, Ultherapy Prime is designed to lift the face, jawline, and chin. This non-surgical facelift program helps tighten skin and define the jawline. Ultherapy Prime is ideal for treating sagging skin and undefined jawlines. The device provides real-time visualization of skin layers for both the face and neck. Ultherapy Prime is perfect for those seeking a facelift without downtime, and it helps treat sagging skin in the cheeks, chin, and neck.

Ultherapy Prime It is a technology. MFU-V Ultherapy Prime uses microfocused ultrasound with real-time visualization to precisely deliver energy to collagen-containing tissue layers, resulting in non-surgical lifting and tightening. According to Ultherapy Prime's documentation, it's an FDA-cleared non-invasive treatment for lifting eyebrows, submental/neck tissue, and improving the appearance of décolletage wrinkles. The real-time visualization allows the doctor to see the skin layers and select the appropriate depth for each individual.

XTherma is a skin tightening device using Monopolar RF technology, administered by expert physicians at Fresh Code Clinic, for lifting and firming the facial contours, reducing sagging, and stimulating collagen production.

part XTherma Fresh Code Clinic offers a skin tightening program. Monopolar RF Equipped with a cooling system, the clinic's menu explains that this treatment uses heat energy deep into the skin layers to stimulate natural collagen production, resulting in gradually firmer, tighter, and smoother skin. It's suitable for those with early to moderate skin sagging who want a non-surgical option with no long downtime.

Therefore, if we look at it from a mechanical perspective...

  • Botox = Treats "muscles," or in some cases, used intradermal for skin improvement.
  • Ultherapy Prime = Treats sagging and tightens skin structure via ultrasound.
  • XTherma = Manages "skin firmness and quality" through Monopolar RF.

Because the functions are different, that's why many people can work together, because it's not entirely repetitive, but rather complements different dimensions of facial problems.

Why do so many people want to do it together?

In real life, many patients don't just have one problem, such as only forehead wrinkles or sagging cheeks, but several issues simultaneously, such as:

  • Wrinkles caused by muscle movement.
  • The skin is starting to sag.
  • The facial features are blurry.
  • My skin doesn't feel as firm as before.
  • Pores appear visible.
  • I want my face to look fresher without changing my facial structure too much.

If using Botox alone, it might only be effective for dynamic wrinkles or specific muscle areas.
If using Ultherapy Prime or XTherma alone, it may help with lifting, tightening, and skin quality, but it does not directly replace Botox for wrinkles caused by facial expressions.

This is why in today's aesthetic world there is a concept... multimodal treatment Alternatively, planning multiple procedures together can lead to more balanced results than using a single tool to solve everything. An article from an expert panel in the Asia-Pacific region clearly reflects this concept, recommending an "inside-out" treatment plan design—looking at the deep structure first, then following with superficial layers or other modalities that help to enhance the outcome.

Can Botox be combined with Ulthera Prime?

The answer is... It can be done in many cases. But it's important to understand the conditions correctly.

Based on the guidelines from the expert panel, it has been stated that: MFU-V can be included in the same plan as BoNT. And if doing it on the same day, it is recommended to... Perform MFU-V first before injectable solution.

However, on the other hand, the Ultherapy Prime case series conducted on Asian patients did not study those who had recently been exposed to neurotoxins in the area. Lower face or neck within 6 months. Furthermore, participants were instructed to refrain from procedures on the face and upper neck for 90 days after the procedure. Therefore, it can be interpreted with caution that if procedures are performed in very close proximity to the lower face/neck, the timing of the treatments should be seriously considered, and it should not be assumed that anyone can have them done consecutively without evaluation.

Therefore, if we ask in a practical way for a website...

  • We can work together on the plan.
  • If so, same-day The supported approach is: Apply Ultherapy Prime first, then Botox.
  • If it's in this area... lower face/neck Or, in complex cases, the doctor should consider the spacing and sequence based on the actual goals of the face.

Can Botox be combined with XTherma?

for XTherma “"In many cases, they can be done together."” Because Botox relaxes certain muscles, while XTherma stimulates collagen production, the order of administration should be evaluated by a doctor for balanced results.

This point is very easy to communicate to the reader because it shows that the two procedures are not competing with each other, but rather playing different roles.

  • Botox = Controls muscle movement in certain areas.
  • XTherma = Stimulates collagen production and tightens skin using Monopolar RF energy.

If the patient's goal is to make their face look fresher but still natural, without drastically altering their facial structure, combining XTherma with Botox is a common practice, especially when the doctor wants to balance both "movement" and "skin quality" simultaneously.

However, the clinic does not have a fixed formula for what to do first for everyone, but emphasizes that the order should be assessed by the doctor, which is a safer and more accurate way of communicating than saying that everyone must do the same thing.

If you're doing them together, which one should you do first?

This is the main question of the article, and it's the point where readers want the clearest answer.

Botox + Ulthera Prime Case

If done in... same-day treatment And it's part of the same plan, with published guidance from an expert panel stating that...
Perform MFU-V first, then proceed with injectable treatments such as BoNT.

The underlying principle is that MFU-V is a deep-layer treatment and one of the modalities that is often applied "inside-out," meaning that deep structures are addressed first. Once the deep-layer treatment is complete, injectable fillers can be added to fine-tune specific areas related to muscle or skin quality afterward.

So, if you ask in a way that's immediately applicable...
Ulthera Prime vs. Botox: If done on the same day, Ulthera Prime is usually done first.

Ultherapy Prime before and after review: Results of face and eyebrow lifting using Microfocused Ultrasound technology at Fresh Code Clinic.
Ultherapy Prime before and after review: Results of face and eyebrow lifting using Microfocused Ultrasound technology at Fresh Code Clinic.
Ultherapy Prime before and after review: Results of face and eyebrow lifting using Microfocused Ultrasound technology at Fresh Code Clinic.

Botox + Xtherma case

Regarding XTherma, the Fresh Code documentation only states that it is “can be used in combination in many cases” and “the sequence should be evaluated by a physician.”
Therefore, to answer honestly and without exaggerating the information:

XTherma and Botox: Can be used together, but the order should depend on the area being treated and the patient's goals.

To explain it in a simpler way.

  • If the primary goal is skin tightening/improving skin quality, the doctor may choose an energy-based treatment as a starting point.
  • If the primary goal is dynamic muscle/wrinkle control, the doctor might prioritize Botox in the treatment plan.
  • If someone is having multiple areas treated simultaneously, such as the upper and lower face having different problems, the same order of action may not apply to every area.

In other words, XTherma's "do it first" approach doesn't have a single answer that works for every situation.

Before and After XTherma skin tightening treatment helps lift and firm the facial contours, reduce double chin, and stimulate collagen production under the skin. Performed by doctors at Fresh Code Clinic, Bangkok.
Before and After XTherma skin tightening treatment helps lift and firm the facial contours, reduce double chin, and stimulate collagen production under the skin. Performed by doctors at Fresh Code Clinic, Bangkok.
Before and After XTherma skin tightening treatment helps lift and firm the facial contours, reduce double chin, and stimulate collagen production under the skin. Performed by doctors at Fresh Code Clinic, Bangkok.

If I don't do them on the same day, how long should I wait?

For this side. MFU-V / Ultherapy Prime A practical guide article from the Asia-Pacific region indicates that if planning a stepwise treatment, multiple sessions can be spaced out. 1–4 weeks To allow local side effects to subside and assess the response before the next session.

Furthermore, the same guideline states that the sequence of modality depends on several factors, such as the patient's primary complaint, skin condition, and the goals of the treatment plan, and is not determined solely by the device used.

Therefore, to write this in a simple way for the web, it can be summarized as follows:

  • If done on the same day as... Ulthera Prime → Ulthera Prime is usually done first, followed by Botox.
  • If done on different days → The doctor may space out the treatments to several weeks to observe the response and plan further steps.
  • If so, XTherma → The sequence and spacing should be assessed individually based on the area and objectives.

Will Botox be affected by "heat" or "energy"?

This is a question patients ask very often because they worry that if they get Botox injections and then undergo a skin tightening procedure afterward, the effects of the Botox will be reduced.

This shouldn't be decided based on feelings, but rather the doctor should prioritize the procedures based on the area to be treated and the chosen procedure. This is especially true if the procedure is performed in close proximity, or on the lower face/neck, where muscle structure, skin structure, and the purpose of the treatment are all involved.

What we can say from the published guidance is: Performing MFU-V and injectable treatments on the same day can be included in the same plan, but it is recommended to do MFU-V first. No additional adverse effects were found from the same-day combination, according to the review.

If you're concerned about forehead wrinkles but also want to lift your jawline, where should you start?

If the main problem is... Wrinkles caused by muscle movement. For example, the forehead, between the eyebrows, and the corners of the eyes. At the same time, people may want to define their facial contours or improve the appearance of sagging cheeks. Combining Botox with Ulthera Prime or Xtherma in the same treatment plan is common because each addresses different layers of the problem.

The simple idea is:

  • If the main concern is... movement Botox is often the key treatment for that area.
  • If the main concern is... laxity / tightness / skin quality → Ulthera Prime or XTherma will play a more significant role.

Often, the answer isn't "choose one," but "prioritize to suit the entire face," which is why a doctor's evaluation is more important than relying solely on other people's reviews.

Before and after Botox results for wrinkle reduction and facial contouring. Before and after Botox for reducing forehead wrinkles, frown lines, and crow's feet. Before and after Botox images for a smoother-looking face. Botox before and after for wrinkle reduction and a sharper facial contour. Before and after Botox results for those concerned about wrinkles and facial shape. Botox before and after for smoother-looking skin and a more defined jawline. Before and after Botox for forehead lines, frown lines, and crow's feet. Botox before and after results for facial lines and a softer appearance. Before and after Botox for wrinkle reduction and facial contour refinement. Botox before and after for a smoother, more refreshed look.
Before and after Botox results for wrinkle reduction and facial contouring. Before and after Botox for reducing forehead wrinkles, frown lines, and crow's feet. Before and after Botox images for a smoother-looking face. Botox before and after for wrinkle reduction and a sharper facial contour. Before and after Botox results for those concerned about wrinkles and facial shape. Botox before and after for smoother-looking skin and a more defined jawline. Before and after Botox for forehead lines, frown lines, and crow's feet. Botox before and after results for facial lines and a softer appearance. Before and after Botox for wrinkle reduction and facial contour refinement. Botox before and after for a smoother, more refreshed look.
Before and after Botox results for wrinkle reduction and facial contouring. Before and after Botox for reducing forehead wrinkles, frown lines, and crow's feet. Before and after Botox images for a smoother-looking face. Botox before and after for wrinkle reduction and a sharper facial contour. Before and after Botox results for those concerned about wrinkles and facial shape. Botox before and after for smoother-looking skin and a more defined jawline. Before and after Botox for forehead lines, frown lines, and crow's feet. Botox before and after results for facial lines and a softer appearance. Before and after Botox for wrinkle reduction and facial contour refinement. Botox before and after for a smoother, more refreshed look.

What if the main concern is the lower face, jawline, and double chin?

This case is more detailed because it's an area where Ultherapy Prime has direct supporting data for lifting/tightening the jawline, submental area, and neck. Furthermore, a case series in Asia showed improvement in neck volume and jawline at 90 days post-treatment in most participants.

Meanwhile, the lower face and neck were areas that the Ultherapy Prime research "excluded" from patients with neurotoxins within 6 months prior to treatment in the lower face/neck.

So, if the patient asks:
“"I've already had Botox for my lower face/masseter, can I do Ulthera Prime right away?"”
The responsible answer is: You shouldn't guess based on information from the internet; you should have a doctor evaluate your actual case first. Because this area is more important in terms of both goals and timing than the general area.

XTherma is similar; it's indicated as suitable for mild to moderate sagging, unclear facial contours, slight cheek sagging, and can be combined with Botox in many cases, but the order of treatment needs to be assessed by a doctor.

In summary, who is right for which plan?

To make it easier for web readers to make decisions, try looking at it this way:

If you're prone to wrinkles from muscle movement...

For example, the forehead, between the eyebrows, and the corners of the eyes, but I'm not yet worried about the sagging being very noticeable.
Botox could be a primary starting point, and if further skin firmness or lifting in specific areas is desired, Ulthera Prime or XTherma can be added to the plan based on assessment.

If you're concerned about sagging skin, an undefined jawline, and drooping cheeks...

Ulthera Prime or Xtherma often plays a more prominent role as the primary treatment, followed by Botox injections if there are dynamic lines or specific muscle areas that need adjustment as well.

If you have both wrinkles and sagging skin at the same time.

These are the groups that typically benefit most from combination plans, but the prioritization should depend on each individual's area and goal; the same formula shouldn't be used for everyone.

What are some things you shouldn't do?

The absolute worst thing to do is... I read the reviews and ranked them myself without evaluating the treatment area. Especially in people who...

  • I just had injections in my lower face/neck.
  • I'm about to perform an energy-based treatment in the same area.
  • There are several overlapping concerns, such as masseter, jawline, submental, and skin texture.
  • I'm not sure which result you want first.

Because even though the general answer is "it can be done together," the word "can" in aesthetic medicine needs further interpretation.
For whom, in which area, how long should it be spaced, and what results are desired?

Simple summary

If you want the shortest answer for memorization.

  • Botox + Ulthera Prime Collaborative planning is possible in many cases.
  • If you do The same day There is published guidance suggesting that: Do Ulthera Prime (MFU-V) first, then proceed with Botox.
  • Ultherapy Prime research in Asia. No studies were conducted on individuals with neurotoxins in the lower face/neck area within 6 months prior to the procedure. Therefore, it is even more important to have a doctor assess the timing, especially if it is a lower face/neck injury.
  • Botox + XTherma It can be done together in many cases.
  • but The sequence of treatments for XTherma and Botox should be evaluated by a doctor. Because it depends on the goal, the area being treated, and the balance of the face.

To summarize once again:
You can do it together, but you shouldn't copy other people's timing and use it on your own face.

FAQ (Frequently Asked Questions)

Can I get Botox injections along with Ulthera Prime?

This is possible in many cases, and if done on the same day, published guidance recommends doing MFU-V or Ulthera Prime first, followed by injectable substances such as Botox.

Can I get Botox injections along with XTherma injections?

In many cases, both treatments can be used together, as Botox relaxes certain muscles while XTherma stimulates collagen production. However, the order of treatment should be assessed by a doctor for balanced results.

If we're doing them on the same day, which one should we do first?

For Ulthera Prime, the recommendation is clearer: do MFU-V first, then Botox. As for Xtherma, there's no fixed formula for everyone based on the information provided, so it should depend on the doctor's assessment.

If I've recently had Botox injections in my lower face or neck, can I do Ulthera Prime right away?

A medical evaluation is recommended first, as Ultherapy Prime case series in Asia has excluded patients with neurotoxins in the lower face or neck within 6 months prior to treatment. Therefore, it should not be assumed that every case can be treated consecutively.

If you have both wrinkles and sagging skin, should you choose to do just one treatment or both?

Depending on whether the primary problem is muscle or skin laxity, a combination of both may be more effective if both are present. However, it's best to have a doctor design a treatment sequence and areas tailored to your specific facial needs.

If you are hesitating about whether... Which combination is best suited for Botox: Ulthera Prime or XTherma? Or perhaps you're unsure where to start with your own face? Fresh Code Clinic We recommend evaluating the model. case by case Before anything else, because effective skin tightening isn't just about choosing the right device or injections, but about prioritizing the treatments according to each individual's facial structure, goals, and skin condition.

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